E. Szegezdi, S. E. Logue, A. M. Gorman, and A. Samali, Mediators of endoplasmic reticulum stress-induced apoptosis, Embo Rep, vol.7, pp.880-885, 2006.

M. Wang and R. J. Kaufman, Protein misfolding in the endoplasmic reticulum as a conduit to human disease, Nature, vol.529, pp.326-335, 2016.

I. M. Wortel, L. T. Van-der-meer, M. S. Kilberg, and F. N. Van-leeuwen, Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells, Trends Endocrinol. Metab. Tem, vol.28, pp.794-806, 2017.

J. Han, S. H. Back, J. Hur, Y. H. Lin, R. Gildersleeve et al., ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death, Nat. Cell Biol, vol.15, pp.481-490, 2013.

S. J. Marciniak, C. Y. Yun, S. Oyadomari, I. Novoa, Y. Zhang et al., CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum, Genes Dev, vol.18, pp.3066-3077, 2004.

S. B. Cullinan, D. Zhang, M. Hannink, E. Arvisais, R. J. Kaufman et al., Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival, Mol. Cell. Biol, vol.23, pp.7198-7209, 2003.

J. M. Hourihan, L. E. Moronetti-mazzeo, L. P. Fernandez-cardenas, and T. K. Blackwell, Cysteine Sulfenylation Directs IRE-1 to Activate the SKN-1/Nrf2 Antioxidant Response, Mol. Cell, vol.63, pp.553-566, 2016.

G. M. Denicola, F. A. Karreth, T. J. Humpton, A. Gopinathan, C. Wei et al., Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis, Nature, vol.475, pp.106-109, 2011.

S. Tao, S. Wang, S. J. Moghaddam, A. Ooi, E. Chapman et al., Oncogenic KRAS confers chemoresistance by upregulating NRF2, Cancer Res, vol.74, pp.7430-7441, 2014.

C. Tonelli, I. I. Chio, and D. A. Tuveson, Transcriptional Regulation by Nrf2, Antioxid. Redox Signal, 2017.

S. Wang, X. A. Chen, J. Hu, J. K. Jiang, Y. Li et al., ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells, Mol. Cancer, vol.14, pp.877-888, 2015.

P. D. Lu, C. Jousse, S. J. Marciniak, Y. Zhang, I. Novoa et al., Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2, Embo J, vol.23, pp.169-179, 2004.

M. D. Shoulders, L. M. Ryno, J. C. Genereux, J. J. Moresco, P. G. Tu et al., Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments, Cell Rep, vol.3, pp.1279-1292, 2013.

E. K. Schmidt, G. Clavarino, M. Ceppi, and P. Pierre, SUnSET, a nonradioactive method to monitor protein synthesis, Nat. Methods, vol.6, pp.275-277, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00408410

S. Dey, C. M. Sayers, I. I. Verginadis, S. L. Lehman, Y. Cheng et al., ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis, J. Clin. Investig, vol.125, pp.2592-2608, 2015.

N. A. Smirnova, R. E. Haskew-layton, M. Basso, D. M. Hushpulian, J. B. Payappilly et al., Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators, Chem. Biol, vol.18, pp.752-765, 2011.

C. Jousse, A. Bruhat, H. P. Harding, M. Ferrara, D. Ron et al., Amino acid limitation regulates CHOP expression through a specific pathway independent of the unfolded protein response, Febs Lett, vol.448, pp.211-216, 1999.

T. Iso, T. Suzuki, L. Baird, and M. Yamamoto, Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells, Mol. Cell. Biol, vol.36, pp.3100-3112, 2016.