In Vivo Quantitative Prediction of the Effect of Gene Polymorphisms and Drug Interactions on Drug Exposure for CYP2C19 Substrates

Sylvain Goutelle 1 L. Bourguignon Nathalie Bleyzac 2 J. Berry F. Clavel-Grabit M. Tod
1 Evaluation et modélisation des effets thérapeutiques
Département biostatistiques et modélisation pour la santé et l'environnement [LBBE]
2 Département biostatistiques et modélisation pour la santé et l'environnement [LBBE]
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https://hal-univ-lyon1.archives-ouvertes.fr/hal-02401797
Contributor : Marie-Gabrielle Chautard <>
Submitted on : Tuesday, December 10, 2019 - 11:03:49 AM
Last modification on : Monday, February 10, 2020 - 4:36:58 PM

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Sylvain Goutelle, L. Bourguignon, Nathalie Bleyzac, J. Berry, F. Clavel-Grabit, et al.. In Vivo Quantitative Prediction of the Effect of Gene Polymorphisms and Drug Interactions on Drug Exposure for CYP2C19 Substrates. AAPS Journal, American Association of Pharmaceutical Scientists, 2013, 15, pp.415-26. ⟨10.1208/s12248-012-9431-9⟩. ⟨hal-02401797⟩

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