Elemental imaging using laser-induced breakdown spectroscopy: latest medical applications

Abstract : Multi-elemental imaging of soft tissues using Laser-induced breakdown spectroscopy, also known as LIBS, allows for the direct visualization of the distribution of endogenous or exogenous elements within tissues. LIBS was used to image the kinetics of metal nanoparticles in elimination organs, but also the physiological distribution of biological elements in situ and the topography of chemicals or metals in exposed human tissues. Based on our experience and recent literature in the field of imaging the elemental content of animal and human specimens, this review describes the principle and characteristics of the instrument, technical considerations for setting up experiments with LIBS, its advantages, limitations and possibilities for pre-clinical and medical applications.
Document type :
Journal articles
Complete list of metadatas

Cited literature [22 references]  Display  Hide  Download

https://hal-univ-lyon1.archives-ouvertes.fr/hal-02367671
Contributor : Armelle Vidal <>
Submitted on : Tuesday, January 14, 2020 - 1:32:53 PM
Last modification on : Tuesday, January 21, 2020 - 1:07:41 AM

File

msc190133.pdf
Publisher files allowed on an open archive

Identifiers

Collections

Citation

Marine Leprince, Lucie Sancey, Jean-Luc Coll, Vincent Motto-Ros, Benoît Busser. Elemental imaging using laser-induced breakdown spectroscopy: latest medical applications. médecine/sciences, EDP Sciences, 2019, 35 (8-9), pp.682-688. ⟨10.1051/medsci/2019132⟩. ⟨hal-02367671⟩

Share

Metrics

Record views

37

Files downloads

27