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Journal articles
Advancing Solutions to the Carbohydrate Sequencing Challenge
Abstract : Carbohydrates possess a variety of distinct features with stereochemistry playing a particularly important role in distinguishing their structure and function. Monosaccharide building blocks are defined by a high density of chiral centers. Additionally, the anomericity and regiochemistry of the glycosidic linkages carry important biological information. Any carbohydrate-sequencing method needs to be precise in determining all aspects of this stereodiversity. Recently, several advances have been made in developing fast and precise analytical techniques that have the potential to address the stereochemical complexity of carbohydrates. This perspective seeks to provide an overview of some of these emerging techniques, focusing on those that are based on NMR and MS-hybridized technologies including ion mobility spectrometry and IR spectroscopy.
https://hal-univ-lyon1.archives-ouvertes.fr/hal-02365096
Contributor : Armelle Vidal Connect in order to contact the contributor
Submitted on : Wednesday, January 20, 2021 - 9:50:34 AM
Last modification on : Friday, January 7, 2022 - 3:44:56 AM
Long-term archiving on: : Wednesday, April 21, 2021 - 6:15:59 PM
Contributor : Armelle Vidal Connect in order to contact the contributor
Submitted on : Wednesday, January 20, 2021 - 9:50:34 AM
Last modification on : Friday, January 7, 2022 - 3:44:56 AM
Long-term archiving on: : Wednesday, April 21, 2021 - 6:15:59 PM
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