Skip to Main content Skip to Navigation
Journal articles

Mixed Mechanism of Lubrication by Lipid Bilayer Stacks.

Abstract : Although the key role of lipid bilayer stacks in biological lubrication is generally accepted, the mechanisms underlying their extreme efficiency remain elusive. In this article, we report molecular dynamics simulations of lipid bilayer stacks undergoing load and shear. When the hydration level is reduced, the velocity accommodation mechanism changes from viscous shear in hydration water to interlayer sliding in the bilayers. This enables stacks of hydrated lipid bilayers to act as efficient boundary lubricants for various hydration conditions, structures, and mechanical loads. We also propose an estimation for the friction coefficient; thanks to the strong hydration forces between lipid bilayers, the high local viscosity is not in contradiction with low friction coefficients.
Document type :
Journal articles
Complete list of metadata

https://hal-univ-lyon1.archives-ouvertes.fr/hal-02308161
Contributor : Depot 4 Lyon 1 <>
Submitted on : Tuesday, October 8, 2019 - 12:56:47 PM
Last modification on : Saturday, January 30, 2021 - 3:29:44 AM

Identifiers

Collections

Citation

Alexandru Botan, Laurent Joly, Nicolas Fillot, Claire Loison. Mixed Mechanism of Lubrication by Lipid Bilayer Stacks.. Langmuir, American Chemical Society, 2015, 31 (44), pp.12197-202. ⟨10.1021/acs.langmuir.5b02786⟩. ⟨hal-02308161⟩

Share

Metrics

Record views

55