Eosinophilic Lung Diseases

Vincent Cottin (1)

1 IVPC - Infections Virales et Pathologie Comparée - UMR 754

Eosinophilic lung diseases especially comprise eosinophilic pneumonia or as the more transient Loffler syndrome, which is most often due to parasitic infections. The diagnosis of eosinophilic pneumonia is based on characteristic clinical-imaging features and the demonstration of alveolar eosinophilia, defined as at least 25% eosinophils at BAL. Peripheral blood eosinophilia is common but may be absent at presentation in idiopathic acute eosinophilic pneumonia, which may be misdiagnosed as severe infectious pneumonia. All possible causes of eosinophilia, including drug, toxin, fungus related etiologies, must be thoroughly investigated. Extrathoracic manifestations should raise the suspicion of eosinophilic granulomatosis with polyangiitis.

Mots clés: Humans; Chronic Disease; Smoking; Lung Diseases; Diagnosis; Differential; Bronchoalveolar Lavage; Acute Disease; Allergic Bronchopulmonary/*diagnosis/immunology/therapy; Aspergillosis; Asthma/diagnosis/immunology/therapy; Churg-Strauss Syndrome/*diagnosis; Eosinophilia/complications/*diagnosis/immunology; Parasitic/*diagnosis/immunology/therapy; Pulmonary Eosinophilia/complications/*diagnosis/immunology/therapy

Domaines: Sciences du Vivant [q-bio]

Vincent Cottin. Eosinophilic Lung Diseases. Clinics in Chest Medicine, 2016, 37 (3), pp.535-56. ⟨10.1016/j.ccm.2016.04.015⟩. ⟨hal-02192925⟩