Further insight in the minor/major concept using hydrogen pressure effect in asymmetric hydrogenation

A. Aloui 1, 2 F. Delbecq 2 P. Sautet 2 C. de Bellefon 1
1 LGPC - Laboratoire de Génie des Procédés Catalytiques
2 LC - Laboratoire de Chimie - UMR5182
Abstract : The catalytic system prepared from [Rh(COD)(2)]BF4 and (R,R)-Me-BPE provides a spectacular detrimental hydrogen pressure effect on ee from 94% down to 56% in the hydrogenation of methylacrylate, whereas it has a strong beneficial effect on the hydrogenation of E-emap (from 42% up to 72%). The kinetic parameters have been determined for both systems and have helped to identify the most enantioselective controlling steps (MECS). Accordingly, further explanations for the structure-ee and hydrogen pressure relationship are proposed. (c) 2012 Elsevier B.V. All rights reserved.
Document type :
Journal articles
Complete list of metadatas
https://hal-univ-lyon1.archives-ouvertes.fr/hal-01923743
Contributor : Lauriane Pillet <>
Submitted on : Thursday, November 15, 2018 - 2:02:28 PM
Last modification on : Thursday, November 21, 2019 - 1:51:46 AM

Identifiers

Collections

UNIV-LYON1 | CNRS | ENS-LYON | INC-CNRS | HAL-CHIMIE-ENSLYON | UDL

Citation

A. Aloui, F. Delbecq, P. Sautet, C. de Bellefon. Further insight in the minor/major concept using hydrogen pressure effect in asymmetric hydrogenation. Journal of Molecular Catalysis A: Chemical, Elsevier, 2012, 363-364, pp.214 - 222. ⟨10.1016/j.molcata.2012.06.012⟩. ⟨hal-01923743⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

60

Contact

Informations

CCSD