Correlates of adherence to respiratory drugs in COPD patients

L. Laforest; Francois Denis; Eric van Ganse; Cecile Ritleng; Christel Saussier; Nadine Passante; Gilles Devouassoux; Gerard Chatté; Nathalie Freymond; Yves Pacheco

Correlates of adherence to respiratory drugs in COPD patients

L. Laforest ¹ Francois Denis ² Eric van Ganse Cecile Ritleng Christel Saussier Nadine Passante Gilles Devouassoux ³ Gerard Chatté Nathalie Freymond ⁴ Yves Pacheco ⁵

1 HESPER - Health Service and Performance Research

2 LIF - Laboratoire d'informatique Fondamentale de Marseille - UMR 6166

3 Service de Pneumologie

4 CHLS - Centre Hospitalier Lyon Sud [CHU - HCL]

5 Immunovirologie et polymorphisme génétique

Abstract : AIMS: To identify the correlates of accidental omissions and intentional interruptions of respiratory therapy in COPD. METHODS: COPD patients (GOLD stages II-IV) were recruited by general practitioners or respiratory physicians. Patients reported in self-report questionnaires their adherence to respiratory drugs (over the past three months) and their perception of therapy. RESULTS: 179 patients were included (mean age 63 years, 24% females). 45% forgot their respiratory therapy, while 30% interrupted it in the absence of any perceived benefit. The risks of accidental omissions were significantly higher when patients complained about having too many medications to take on a daily basis (OR=2.35; 95%CI=1.13-4.89), and among current smokers (OR=2.14; 95%CI=1.07-4.29). Females were more likely to interrupt therapy intentionally (OR=2.40; 95%CI=1.04-5.53). Surprisingly, there was no significant relationship with the number of drugs actually taken by patients. CONCLUSIONS: Adherence to respiratory drugs is inadequate in COPD patients. In order to improve adherence, patients' perception of the burden of therapy should not be overlooked.

Keywords : Female Humans Male Aged Middle Aged Adult Multivariate Analysis Logistic Models Age Factors Severity of Illness Index Sex Factors Cross-Sectional Studies Smoking Chronic Obstructive Medication Adherence Pulmonary Disease Respiratory System Agents

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Santé publique et épidémiologie

Complete list of metadatas

https://hal-univ-lyon1.archives-ouvertes.fr/hal-01838988
Contributor : Christelle Cheval <>
Submitted on : Friday, July 13, 2018 - 4:45:52 PM
Last modification on : Saturday, July 14, 2018 - 1:21:00 AM

Correlates of adherence to respiratory drugs in COPD patients

Identifiers

Collections

Citation

Export

Metrics

73

Contact

Correlates of adherence to respiratory drugs in COPD patients

Identifiers

Collections

Citation

Export

Share

Metrics

73

Contact