From Single-Scale to Multiscale Modelling in Biology

Samuel Bernard 1, 2
1 DRACULA - Multi-scale modelling of cell dynamics : application to hematopoiesis
ICJ - Institut Camille Jordan [Villeurbanne], Inria Grenoble - Rhône-Alpes, CGPhiMC - Centre de génétique et de physiologie moléculaire et cellulaire
Abstract : : Biological processes span several scales in space, from the single molecules to organisms and ecosystems. Multiscale modelling approaches in biology are useful to take into account the complex interactions between different organisation levels in those systems. We review several single- and multiscale models, from the most simple to the complex ones, and discuss their properties from a multiscale point of view. Approaches based on master equations for stochastic processes, individual-based models, hybrid continuous-discrete models and structured PDE models are presented.
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Samuel Bernard. From Single-Scale to Multiscale Modelling in Biology. Acta Biotheoretica, Springer Verlag, 2013, 61 (3), pp.291-303. ⟨10.1007/s10441-013-9199-z⟩. ⟨hal-00867564⟩



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