Magnetic polymers for magnetophoretic separation in microfluidic devices

Lucie Descamps (1, 2, 3) , Damien Le Roy (4) , Caterina Tomba (2) , Anne-Laure Deman (2)

1 CREAB - Chimie pour la Reconnaissance et l’Etude d’Assemblages Biologiques
2 INL - Institut des Nanotechnologies de Lyon
3 DIESE - Département Interfaces pour l'énergie, la Santé et l'Environnement
4 MAGNETIQUES - Nanostructures magnétiques

Magnetophoresis offers many advantages for manipulating magnetic targets in microsystems. The integration of micro-flux concentrators and micro-magnets allows achieving large field gradients and therefore large reachable magnetic forces. However, the associated fabrication techniques are often complex and costly, and besides, they put specific constraints on the geometries. Magnetic composite polymers provide a promising alternative in terms of simplicity and fabrication costs, and they open new perspectives for the microstructuring, design, and integration of magnetic functions. In this review, we propose a state of the art of research works implementing magnetic polymers to trap or sort magnetic micro-beads or magnetically labeled cells in microfluidic devices.

Mots clés: magnetic polymers; polymer composites; magnetophoresis; micro-bead separation; cell separation; microfluidic devices

Domaines: Polymères; Mécanique des fluides [physics.class-ph]; Micro et nanotechnologies/Microélectronique

Lucie Descamps, Damien Le Roy, Caterina Tomba, Anne-Laure Deman. Magnetic polymers for magnetophoretic separation in microfluidic devices. Magnetochemistry, 2021, 7 (7), pp.100. ⟨10.3390/magnetochemistry7070100⟩. ⟨hal-03335744⟩